New Imaging Technique Offers Hope for Patients with Traumatic Brain Injury

Brain injuries are exceedingly complex, which makes treatment and rehabilitation difficult in many cases. Researchers at the University of Pittsburgh have reported using a new imaging technique called High-Definition Fiber Tracking (HDFT) to identify the disrupted neural pathways (paths made up of brain cells that communicate with one another) in patients with traumatic brain injury.

Visualization of TBI using HDFT

Body Clock Strength Impacts Bipolar Disorder

Bipolar Disorder, also known as manic–depressive disorder, is a condition characterized by alternating states of elevated energy, cognition and mood, with periods of irritable mood and depression. The extreme mood swings experienced by patients with bipolar disorder have been strongly associated with disruptions in circadian rhythms — the 24-hour cycle of biological processes that govern our day and night activity.

Lithium is one of the most common treatments for bipolar disorder. However, little research has been done to find out if and how lithium impacts the brain and peripheral body clockwork. A new study published in the open access journal PLoS ONE reveals a novel link between lithium, bipolar disorder and circadian rhythms [1].

Bipolar Disorder

A Light Switch to Turn Specific Neurons On and Off

Ed Boyden is creating new brains. A pioneer in the field of optogenetics, he is the founder and principal investigator of the synthetic neurobiology group at the MIT Media Lab, which invents technologies to reveal how cognition and emotion arise from brain networks — and to enable systematic repair of disorders such as epilepsy and post-traumatic stress disorder (ptsd).

Using a combination of lasers and genetic engineering, Boyden’s lab implants brains with optical fibers that allow them to activate special proteins in specific neurons and see their connections. In addition to helping create detailed maps of brain circuitry, the engineering of these cells has been used to cure blindness in mice, and could point the way to cures for Parkinson’s disease or Alzheimer’s disease. On the horizon: ways of connecting to the brain via prosthetics.

By inserting genes for light-sensitive proteins into brain cells, neurons can be selectively activated or de-activated with fiber-optic implants. Check out Boyden’s demonstration at TED2011 below.

MyHeartMap Challenge Inspires Pennsylvanians to Map AEDs

The University of Pennsylvania has been conducting a contest — the MyHeartMap Challenge — in which participants record locations of automated external defibrillators (AEDs) throughout the state. The purpose of the contest is to raise awareness about the importance and location of AEDs, and to build a statewide database of AED locations.

MyHeartMap Challenge

Brain Awareness Week 2012 at Highlight HEALTH

Brain Awareness Week (BAW) is an annual celebration, coordinated by the Dana Alliance for Brain Initiatives and the European Dana Alliance for the Brain, dedicated to raising public awareness about the progress and benefits of brain research. Every March, BAW unites the efforts of organizations around the world to bring the excitement of science and communicate the progress and benefits of brain research to the general public.

Brain Awareness Week