At the annual meeting of the American Association for Cancer Research (AACR) last month, researchers from GeneNews Corp. reported that the probability of colorectal cancer (CRC) in asymptomatic patients can be accurately stratified by RNA expression profiling of six genes in whole blood [1]. The company focuses on developing blood-based biomarker tests for the early detection of diseases and personalized health management.
Gene Genie #32 – Googling the Genie
May 25, 2008 | by
Welcome to the 32nd edition of Gene Genie, a blog carnival devoted to genes and genetic conditions. This edition includes some excellent articles on genes and gene-related diseases, genetics, genomics and personalized genetics.
Google Health launched publicly this week and to recognize the event, the last section of the carnival is devoted to articles specifically about the service. Google, financial backer of 23andMe, also funds the Personal Genome Project, which plans to unlock the secrets of common diseases by decoding the DNA of 100,000 people in the world’s biggest gene sequencing project [1]. With the vast number of genetic data points collected for each genome sequenced, a digital system for the movement and storage of personal health information is critical for the widespread use of individualized healthcare. Google’s entrance into the online personal health records market may thus help to accelerate the era of personalized medicine.
With these thoughts in mind, let’s get to this month’s edition of the Genie.
Genomic Medicine: An Educational Resource from Helix Health
May 19, 2008 | by
The Human Genome Project has heralded a new era in our understanding of the molecular basis of disease. Genome-based medicine or personalized medicine is believed to be the future of healthcare. Indeed, genomic medicine is poised to improve disease diagnosis, therapy and prevention.
Although genomics is related to genetics, there is a difference between the two terms. Genetics is the study of single genes and their effects. In contrast, genomics is the study of all the genes in the genome and the interactions among them and their environment. Genetics uses the information from one or two genes to describe a disease state, whereas genomics examines all genetic information to determine biological markers predisposing a person to disease. Genomics is especially relevant for complex or multifactoral disorders such as cancer, Parkinson’s disease, heart disease and diabetes, which are due to the interaction of multiple genes and environmental factors [1].
Remembering Lunch Can Help Reduce the Desire to Snack
May 15, 2008 | by
Mind over matter may really work when it comes to managing appetite. Researchers at the University of Birmingham, U.K. have found that recalling foods eaten at lunch has an inhibitory effect on subsequent snacking later the same day. The study is currently in press and will be published in the journal Physiology & Behavior [1]. The effect was observed regardless of the type of snack eaten or palatability. The study also found that meal recall was only effective in decreasing the amount eaten if participants did not have a tendency to overeat.
Tired? You May Not Be Getting Enough Sleep
May 7, 2008 | by
A good night’s sleep is increasingly loosing out to late night television, the Internet, video games and other modern day distractions, and our health is taking the toll. An estimated 50 to 70 million people suffer from chronic sleep loss and sleep disorders, and loss of sleep is associated with a variety of health problems, including obesity and depression [1]. According to a recent four state study by the Centers for Disease Control and Prevention (CDC), 70% of adults report not getting enough rest or sleep at least once over the past month; 10% report insufficient rest or sleep every day [2].
