The Genetics of Panic Disorder

December 19, 2007 | by

A study published earlier this year in the American Journal of Medical Genetics suggests that lymphoblast gene expression may be used to identify biomarkers for panic disorder. Researchers at the University of Iowa evaluated gene expression profiles in lymphoblasts (immature white blood cells) cultured from patients with and without panic disorder and found specific disorder- and sex-related differences [1]. A blood test for panic disorder and other mental health conditions based on the study results is being developed. However, a commercial diagnostic test may be premature as the study results are far from conclusive.

DNA Amplification by Polymerase Chain Reaction (PCR)

December 12, 2007 | by

What does the diagnosis of hereditary diseases, the detection and diagnosis of infectious diseases, personalized DNA sequencing, DNA cloning, genetic functional analysis, genetic fingerprinting and DNA-based phylogeny have in common?

The all employ a widely used molecular technique called polymerase chain reaction or PCR.

The idea was conceived by Kary Mullis in the early 1980s and was first described, albeit briefly, in an article investigating the mutation that causes sickle cell anemia [1]. The details of the method and its uses were discussed in greater detail over the next two years [2-3]. PCR revolutionized molecular genetics by allowing rapid duplication and analysis of DNA.

Health Highlights – December 10th, 2007

December 10, 2007 | by

Health Highlights is a biweekly summary of particularly interesting articles from credible sources of health and medical information that we follow & read. For a complete list of recommeded sources, see our links page.

Health Highlights

American Obesity Rate Levels Off

December 6, 2007 | by

The Washington Post published a story late last week about obesity in the United States. The story discussed the results of a new study by the Centers for Disease Control and Prevention (CDC). Here’s the article’s opening statement:

The obesity epidemic that has been spreading for more than a quarter-century in the United States has leveled off among women and may have hit a plateau for men …

I was surprised that they use the term “spreading”, since the article fails to mention any of the recent research pertaining to the spread of obesity through social networks.

Social Networks and Health – The Research and the Reviews

December 4, 2007 | by

I’ve been increasingly interested in health-focused social networks. Why? Because several recent scientific studies have found that real-life social networks are quite relevant to health. Indeed, a study published earlier this year in the New England Journal of Medicine evaluated a large social network of over 12,000 people over 32 years to assess the person-to-person spread of obesity [1]. The study results suggest that friends, siblings and spouses have an even greater effect on a person’s risk of obesity than genetics.

What’s interesting is that this type of research is being done now, when the use of web 2.0 services facilitating collaboration and sharing between users on the internet is thriving. We’re witnessing an explosion of social networking sites, many of which are focused on health.