Biomarker Bulletin: March 21, 2011

March 21, 2011 | by

Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.

Biomarker Commons
  • MedTrust Online, Avantra Biosciences Collaborate to Involve Clinicians in Assay Development

    MedTrust Online and Avantra Biosciences recently announced that they will collaborate on involving clinicians in early-stage development of molecular diagnostic assays to run on Avantra Biosciences’ QPDx multiplex immunoassay system.

  • Biomarker May Prove Useful for Diagnosing Knee Injury

    Researchers from Stanford University School of Medicine recently discovered a biomarker that may enable doctors to diagnose a common form of knee injury. The study, published in the Journal of Bone and Joint Surgery, has identified a specific protein complex in the knee fluid of patients with painful meniscal tears.

  • OncoTrack Launches Search for Novel Genomic Cancer Diagnostics

    A new European consortium called OncoTrack has just launched one of Europe’s largest collaborative academic-industry research projects to develop and assess novel approaches for the identification of new biomarkers for colon cancer. The five year project, Methods for systematic next generation oncology biomarker development, brings together top European academic researchers with a wide range of expertise and partners them with pharmaceutical companies.

  • Discovery of Diagnostic and Prognostic Prostate Cancer Serum Biomarkers Guided by Cancer Genetics

    An interdisciplinary team of researchers from ETH Zurich, University Hospital Zurich and the Cantonal Hospital of St. Gallenhas has defined biomarkers in patients’ blood serum that indicates the presence of prostate cancer. The method used has the potential to be applied to other types of tumors.

  • SciClips Launches Diagnostic and Prognostic Biomarker Database

    In the era of personalized medicine, drugs will be targeted to patients based upon his or her unique genetic profile. Biomarkers are a critical component for tailoring treatments to individual patients. Biomarkers will be used as tools for target discovery, noninvasive early stage diagnosis of diseases, for evaluation of mode of action of a drug, dose determination and prediction of the drug effect. They will accelerate not only the development of effective and non-toxic drugs but also help in monitoring patient health and response to treatment.

Biomarker Bulletin: March 7, 2011

March 7, 2011 | by

Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.

Biomarker Commons

Biomarker Bulletin: February 7, 2011

February 7, 2011 | by

Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.

Biomarker Commons
  • Prize4Life Awards $1 Million Prize for Discovery of ALS Biomarker

    Prize4Life, a non-profit organization dedicated to accelerating the discovery of a cure for Amyotrophic Lateral Sclerosis (ALS) by offering incentives to drive innovation, today announced that Dr. Seward Rutkove, Chief of the Division of Neuromuscular Disease at Beth Israel Deaconess Medical Center and Associate Professor of Neurology at Harvard Medical School, has received the $1 million dollar Prize4Life award for the discovery of a new ALS biomarker.

  • Rosetta Genomics Signs Agreements to Advance Development of Body Fluids-Based Diagnostic Tests

    Rosetta Genomics has announced that it has signed two new agreements for the development and validation of microRNA-based diagnostics for various indications related to its Gen 3 products. Rosetta Genomics Gen 3 tests focus on cardiovascular indications, neurodegenerative diseases, women’s health and early detection of certain cancers, and are designed to leverage microRNA biomarkers extracted from body fluids.

  • Genomic Health Announces Results of Biomarker Discovery Program Using Next-Generation Sequencing

    Last week, Genomic Health, Inc. announced that its scientists had successfully used Illumina next-generation sequencing technology to survey expression of the whole human transcriptome and test hypotheses for biomarker discovery in archived tumor and normal breast tissue samples.

  • Spinal Muscular Atrophy Foundation and Rules-Based Medicine Collaborate on SMA Biomarker Panel

    The Spinal Muscular Atrophy (SMA) Foundation and Rules-based Medicine (RBM) have reached the first milestone in a program to develop a panel of plasma protein biomarkers for SMA using RBM’s Multi-Analyte Profiling (MAP) technology platform.

  • Computable Genomix Secures Investment for the Development of Genetic Biomarker Tests

    Memphis-based Computable Genomix announced this week that it has secured an investment from venture capital firm Innova Memphis to pilot a novel process for developing genetic biomarker tests. Leveraging its next-generation computational discovery capability, the company is developing highly targeted genetic biomarker tests for clinical researchers.