Study Identifies Itch-specific Nerves

Scientists have been looking for itch-specific nerves for decades. New research from investigators at Johns Hopkins University and Yale University in the United States and several universities in China has identified sensory neurons in mice that are dedicated to relaying itchy sensations from the top layers of skin to the spinal cord [1].

Woman itching her back

NIH Researchers Implicate Unique Cell Type in Multiple Sclerosis

Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation for treating MS — daclizumab — and could lead to a new class of drugs for treating MS and other autoimmune disorders.

Neuron

Using the Brain to Control Robotic Arms

The BrainGate Company is a privately-held firm focused on the creation of technology that will allow severely disabled individuals, including those with traumatic spinal cord injury and loss of limbs, to communicate and control common everyday functions by thought alone.

The BrainGate neural interface system consists of a sensor to monitor brain signals together with computer software and hardware, which turns brain signals into digital commands for external devices. This is a type of brain-computer interface intended to put robotics and other assistive technology under the brain’s control. The size of a baby aspirin, the sensor contains 100 hair-thin electrodes that can record the activity of small groups of brain cells. It is implanted into the motor cortex, a part of the brain that directs movement.

Mitochondria Dysfunction Occurs Early in Alzheimer’s Disease Prior to Memory Loss, Amyloid Deposits

Mitochondria are specialized subunits inside a cell that produce the cell’s energy and regulate its metabolism. Research suggests that mitochondria may play a central role in neuronal cell survival because they regulate both energy metabolism and cell death pathways. Using genetic mouse models of Alzheimer’s disease, researchers from Mayo Clinic have found that mitochondria in the brain are dysfunctional early in the disease. The findings were recently published in the open access journal PLoS ONE.

Mitochondria

MIT Scientists Demonstrate Memories Reside In Neurons

Neuroscientists — scientists who study the brain — have long attempted to understand the nature of memory. Engrams, or complete memories that are encoded in the brain, now appear to be stored physically as opposed to conceptually, according to research published in the journal Nature [1].

Mouse hippocampus