Safety and Distribution of the H1N1 Influenza Vaccine

November 2, 2009 | by

Know What to Do About the Flu is a webcast series launched by the U.S. Department of Health and Human Services (HHS) to hlep distribute timely and accurate information about the flu. Their goal is to distribute the latest facts and medical guidances so we can all be more effective in combating the spread of the flu and be better prepared should our families, our communities or our workplaces become affected.

In this edition, moderator Lark McCarthy discusses the level of testing prior to the H1N1 influenza A vaccine distribution and the subsequent monitoring that’s planned during and after the phases of distribution with Dr. Bruce Gellin, Director of the National Vaccine Program Office (NVPO) within the HHS, Dr. Jesse Goodman, acting chief scientist with the U.S. Food and Drug Administration (FDA), Dr. Harvey Fineberg, President of the Institute of Medicine (IOM) and Dr. Anne Schuchat, Director of the Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention (CDC).

What You Need to Know About the H1N1 Vaccine

October 1, 2009 | by
H1N1 vaccine

We’ve received a number of questions and concerns about the swine flu and the H1N1 vaccine. Indeed, a new survey by the Harvard School of Public Health finds that six in ten adults are not “absolutely certain” they will get the H1N1 vaccine, citing concerns over side effects, lack of perceived risk and belief that they could receive medication if they do get sick [1]. Just over half of parents surveyed report being “absolutely certain” they well get the vaccine for their children. To help disseminate credible information on the H1N1 vaccine and provide additional sources for review, we’ve put together a list of questions and answers addressing what you need to know about the H1N1 vaccine.

Don’t Get Burned With Your Sunscreen

July 30, 2009 | by

With summer upon us in full force, many people are eager to get out and enjoy some time in the sun. However, prolonged ultraviolet (UV) light exposure poses a threat during summer months. Indeed, for an increasing number of U.S. adults, sunburns are becoming more and more common [1]. Although sunburn can be the immediate result of the sun’s UV rays, repeated overexposure can lead to wrinkles, discoloration and other signs of premature aging of the skin, as well as skin cancer.

Protect yourself from the sun

Sunburn results when the amount of sun exposure exceeds the ability of melanin, the body’s protective pigment, to shield the skin. Using sunscreen regularly is one of the best ways to ensure protection from the sun and avoid skin damage. Sunscreen creates an effective barrier on the skin, absorbing or reflecting the sun’s UV radiation. With all the different sunscreens on the market, have you ever wondered how well your sunscreen works compared to other brands? A recent investigation by the Environmental Working Group (EWG), a non-profit advocacy organization that provides useful health resources to consumers, evaluated 1,620 brand-name sunscreens and found that 60% offer inadequate protection from the sun or contain ingredients with significant safety concerns.

Medpedia: Reliable Crowdsourcing of Health and Medical Information

July 24, 2009 | by

According to a recent survey by the Pew Internet & American Life Project, 61% of adults look online for health information [1]. Surprisingly however, three-quarters of those searching don’t consistently check the source and date of the health reference they find [2]. Indeed, searching for health information online is dangerous and finding credible, up-to-date sources of health information can be a challenge.

Wikipedia is the Web’s most popular free online encyclopedia. If you’ve ever searched for health or medical content online, Wikipedia articles typically appear at or near the top of search engine results. Nevertheless, Wikipedia’s medical entries are prone to manipulation and are not reliable [3]. Moreover, in many cases you don’t know who has contributed content nor their background or expertise.

Wisdom of crowds is the new model for innovation on the Internet in which collective knowledge is thought to be superior to the intelligence of the few. Nevertheless, not all crowds are wise. Recent cases and new research suggests that crowdsourcing is only truly successful when it is focused on a specific task and when the most effective collaborators are involved [4].

Enter Medpedia.

medpedia-logo

The Medpedia Project is a long-term, worldwide initiative to develop an online collaborative source of health and medical information for medical professionals and the general public. A joint effort with Harvard Medical School, Stanford School of Medicine, Berkeley School of Public Health, University of Michigan Medical School and other global health organizations, the intent of Medpedia is to be a repository of up-to-date unbiased medical information, contributed and maintained by health experts around the world and freely available to the general public. Unlike Wikipedia, which allows anyone to modify pages, Medpedia content creators and editors are required to have an M.D., D.O. or Ph.D. in a biomedical field; each contributor has an author page detailing their qualifications and background.

MicroRNAs in Human Health and Disease

July 1, 2009 | by

The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either protein or nucleic acid. The irreversible flow of information is from DNA to RNA to protein; DNA is transcribed into messenger RNA (mRNA) and subsequently translated into protein. However, in recent years it has become clear that additional genetic information exists in the human genome. Non-protein coding RNA (ncRNA) refers to mRNA that is transcribed from DNA but is not translated into protein. These sequences, once thought of as “junk DNA” – portions of the DNA sequence of the genome that don’t have a function – are being found to have crucial roles in human development, physiology and disease. Indeed, recent studies suggest that there are thousands of ncRNAs in the human genome [1-2].

Non-coding RNAs include a class of molecules called microRNAs (miRNAs or miRs). MicroRNAs are highly expressed in normal tissues and are being found to have critical roles in gene regulatory processes during cellular development and differentiation. MicroRNAs are small ncRNAs ~21-nucleotides long that regulate gene expression at the post-transcriptional level. MicroRNAs function by binding target mRNA molecules and either inhibiting translation into protein or targeting them for degradation. Abnormal microRNA expression has been linked to many human diseases, including schizophrenia, autism and cancer.