Blood Stem-Cell Transplant Regimen Reverses Sickle Cell Disease in Adults

A modified blood adult stem-cell transplant regimen has effectively reversed sickle cell disease in 9 of 10 adults who had been severely affected by the disease, according to results of a National Institutes of Health study in the Dec. 10 issue of the New England Journal of Medicine. The trial was conducted at the NIH Clinical Center in Bethesda, Md., by NIH researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), and the National Institute of Allergy and Infectious Diseases.

NIH Launches Program to Develop Innovative Approaches to Combat Obesity

The National Institutes of Health is launching a $37 million program that will use findings from basic research on human behavior to develop more effective interventions to reduce obesity. The program, Translating Basic Behavioral and Social Science Discoveries into Interventions to Reduce Obesity, will fund interdisciplinary teams of researchers at seven research sites. Investigators will conduct experimental research, formative research to increase understanding of populations being studied, small studies known as proof of concept trials, and pilot and feasibility studies to identify promising new avenues for encouraging behaviors that prevent or treat obesity.

Non-Invasive Technique Blocks a Conditioned Fear in Humans

Scientists have for the first time selectively blocked a conditioned fear memory in humans with a behavioral manipulation. Participants remained free of the fear memory for at least a year. The research builds on emerging evidence from animal studies that reactivating an emotional memory opens a 6-hour window of opportunity in which a training procedure can alter it.

Behavioral Training Improves Connectivity and Function in the Brain

Children with poor reading skills who underwent an intensive, six-month training program to improve their reading ability showed increased connectivity in a particular brain region, in addition to making significant gains in reading, according to a study funded in part by the National Institute of Mental Health (NIMH). The study was published in the Dec. 10, 2009, issue of Neuron.

Medpedia Now Includes News & Analysis, Alerts, Q&A

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The Medpedia Project is a long-term, worldwide initiative to develop an online collaborative source of health and medical information for medical professionals and the general public. Launched in February 2009, the website currently has 34,100 pages of health and medical content (based on a Google domain search), an increase of over 2-fold since July 2009.

The Medpedia Project recently announced the addition of three new tools for sharing and advancing medical knowledge [2]. The services complement Medpedia’s reliable crowdsourcing of health and medical information.