Gene Expression Can Predict the Survival of Lymphoma Patients

ResearchBlogging.orgA study published last week in the New England Journal of Medicine identified sets of genes in diffuse large B-cell lymphoma that influence the effectiveness of chemotherapy [1]. Researchers found that the tumor microenvironment, consisting of non-cancerous immune and structural cells along with tumor cells, has a significant influence on a patient’s response to treatment.

Potential Location of Autism Genes Identified

Earlier this month at the 58th Annual Meeting of the American Society of Human Genetics in Philadelphia, researchers reported the results of two genome-wide genetic analyses, identifying five significant loci that contribute to autism susceptibility, three of which have not been reported previously [1], as well as a novel association of genetic variation on chromosome 5 with autism [2].

Autism

New Highlight HEALTH Network RSS Feed

It’s been almost a year since we introduced the Highlight HEALTH Network. The network is an aggregation of content from three sites:

  • Highlight HEALTH
  • Highlight HEALTH 2.0
  • The Highlight HEALTH Web Directory

There’s also a network webpage, Highlight HEALTH.net (.net as in network, creative isn’t it?), which displays recent content from each site. The Highlight HEALTH Network makes it easy to stay up-to-date with the latest articles and directory links, all from a single source.

Health Search and the Semantic Web

Before it gets too far behind us, I wanted to write briefly about the Health 2.0 Conference, which was held in San Francisco on October 22 and 23rd. The Health 2.0 Conference focuses on the application of Web 2.0 technologies to the fields of medicine and healthcare. Specifically, I wanted to comment on health search, the semantic web and the demonstration of the health 2.0 service iMedix.

Search engines today rely extensively on keywords. However, with health-related searches, context or meaning takes on great importance. Consider this: a study earlier this summer found that simply replacing the search term “vaccine safety” with “vaccine danger” replaced virtually all accurate search results (out of the first 20) with inaccurate results [1]. Granted, there are several limitations to the study (small sample size, controversial topic), but it nonetheless illustrates how a single keyword can dramatically alter search results.

Encephalon #58 – Decision Making

Welcome to the 58th edition of Encephalon, where we highlight some of the best neuroscience and psychology blog posts from around the blogosphere. This edition includes 20 articles on a variety of interesting topics, including intelligence, belief, neurodegeneration, multi-tasking, memory, grief and consciousness.

There’s a revolution occurring on the Web: those “authoritative” articles written on traditional, static websites are being replaced with blogs, wikis and online social networks. In the sphere of health, medicine and information technology, this “real-time Web” consists of many who are professionals in the field; their posts are listed below.
In the digital age, these are the characteristics of new media: recent, relevant, reachable and reliable.

This edition of Encephalon coincides with the historic 44th U.S. Presidential election. As with every election, voters had to decide which candidate for whom to cast their ballot. Although a recent brain-imaging study found that voting decisions are more associated with the brain’s response to negative aspects of a politician’s appearance than to positive ones [1], many other sources of information come into play when we make important and complex decisions. Indeed, studies have shown that decision making is largely an unconscious process [2], in which a set of attributes, including needs, preferences, values and emotions, shape our response to sensory input.

Will there be engaging and thought-provoking articles below? Will each of us learn something new as we read through the posts? Will this edition of Encephalon be successful?

Let’s move through each of the attributes and shape our response to these questions.