Viral-based Human Disease and the Nobel Prize for Medicine

nobel medal in medicineThe 2008 Nobel Prize in Physiology or Medicine was announced earlier this week. The prize was awarded to three europeans for the discoveries of two viruses that cause severe human disease; the cancer-causing human papilloma virus (HPV) and the human immunodeficiency virus (HIV).

Two French scientists, Luc Montagnier, age 76, at the University of Paris in Paris, France and Francoise Barré-Sinoussi, age 61, at the Institut Pasteur in Garches, France will split half the prize for their discovery of the HIV virus. Barré-Sinoussi is the 8th woman to receive the Nobel award for Physiology or Medicine.

A German researcher, Harald zur Hausen, age 72, at the University of Dusseldorf, Germany, will receive the other half of the $1.3 million prize for establishing that most cervical cancers are caused by two types of human papilloma virus.

Health Highlights – October 7th, 2008

Health Highlights is a biweekly summary of particularly interesting articles from credible sources of health and medical information that we follow & read. For a complete list of recommeded sources, see our links page.

Health Highlights

NIH Increases Support for High-risk Large-impact Biomedical Research

The National Institutes of Health (NIH) announced last week that it has increased support for high-risk, large-impact research by awarding 16 investigators the Pioneer Award; 2.5 million for each investigator over five years to pursue research in a variety of areas, including embroyonic development, autism, prions (responsible for the formation of amyloid plaques that lead to neurodegeneration) and malaria [1].

The NIH Director’s Pioneer Award is a high-risk research initiative desiged to [2]:

… support individual scientists of exceptional creativity who propose pioneering — and possibly transforming approaches — to major challenges in biomedical and behavioral research.

First announced in 2004, 9 awards were presented in September 2004, 13 awards each were made in 2005 and 2006, and 12 awards were presented last year.

HelixGene Foundation to Ensure Responsible Reporting of Genomic Medicine

Traditional media (i.e. television, print) are the principal sources of science information for the public. This is changing however; adult home broadband users under the age of 30 report that the internet is the most popular source for science news and information [1]. Unfortunately, while the public is consuming science reporting today more than ever before, the media is doing a poorer job covering the field. This is particularly troublesome for genomic medicine and personal genetics, since many physicians who lack training in genomics and genetics frequently get their information from the same mainstream media sources as the public.

Genomic medicine is the use of information from the genome to guide the development of new therapeutics and directly influence patient care.
Personal genetics is the use of a person’s genetic makeup to predict health risks and provide ancestry information.

Closing Arguments on Big Tobacco, Boston Legal Style

The ABC television drama Boston Legal is one of my favorite programs. The show features quick, intelligent dialogue and great performances. Producer David E. Kelly has used Boston Legal as a platform to speak out on a number of issues over the last four seasons. Each installment walks a fine line between entertainment and political/social issues such as the Iraq War, global warming and Hurricane Katrina. Tuesday night’s season premier titled “Smoke Signals” was no exception. In this episode, Kelly tackles big tobacco.