Traditional ‘Heel Stick’ Test Is Not an Effective Screening Tool for CMV in Newborns

April 13, 2010 | by

A routine screening test for several metabolic and genetic disorders in newborns, the heel-stick procedure, is not effective in screening for cytomegalovirus (CMV) infection, a leading cause of hearing loss in children, according to research published in the April 14 online issue of the Journal of the American Medical Association.

About 20,000-30,000 infants are born infected with CMV each year, 10-15 percent of whom are at risk for eventually developing hearing loss.

The study, funded by the National Institute on Deafness and Other Communication Disorders (NIDCD), one of the National Institutes of Health, is part of a multicenter research project headed by the University of Alabama at Birmingham that is seeking to find the most effective screening test for CMV infection in newborns. The standard method for detecting CMV infection in newborns is labor-intensive and not conducive to a widespread screening program.

World Health Day: 1000 Cities, 1000 Lives

April 8, 2010 | by

Urbanization is one of the greatest health challenges facing with world in the 21st century. Today, over 3 billion people live in cities. Between 1995 and 2005, the urban population of developing countries grew by ~165,000 people every day [1]. In 2007, the world’s population living in cities actually surpassed 50% for the first time in history. As city populations around the world continue to grow, unplanned or mismanaged urbanization can have health security and safety consequences.

1000cities1000lives

Sleep Apnea Tied to Increased Risk of Stroke

April 8, 2010 | by

Obstructive sleep apnea is associated with an increased risk of stroke in middle-aged and older adults, especially men, according to new results from a landmark study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Overall, sleep apnea more than doubles the risk of stroke in men. Obstructive sleep apnea is a common disorder in which the upper airway is intermittently narrowed or blocked, disrupting sleep and breathing during sleep.

Sleep apnea and snoring

Common Mechanisms of Drug Abuse and Obesity

March 31, 2010 | by

Some of the same brain mechanisms that fuel drug addiction in humans accompany the emergence of compulsive eating behaviors and the development of obesity in animals, according to research funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health.

The study, conducted by researchers at the Scripps Research Institute, was released on March 28th in the online version of Nature Neuroscience and will also appear in the journal’s May 2010 print issue. When investigators gave rats access to varying levels of high-fat foods, they found unrestricted availability alone can trigger addiction-like responses in the brain, leading to compulsive eating behaviors and the onset of obesity.

“Drug addiction and obesity are two of the most challenging health problems in the United States,” said Dr. Nora D. Volkow, director of NIDA. “This research opens the door for us to apply some of the knowledge we have gathered about drug addiction to the study of overeating and obesity.”

Both obesity and drug addiction have been linked to a dysfunction in the brain’s reward system. In both cases overconsumption can trigger a gradual increase in the reward threshold — requiring more and more palatable high fat food or reinforcing drug to satisfy the craving over time.

Diet Quality Worsens as Alcohol Intake Increases

March 26, 2010 | by

According to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), and the U.S. Department of Agriculture (USDA), people who drink more are also likely to eat less fruit and consume more calories from a combination of alcoholic beverages and foods high in unhealthy fats and added sugars.

Alcoholic drinks