Blood Protein Linked to Alzheimers Brain Abnormalities

Neuroimaging is one of the most promising research areas for detection of the earliest stages of Alzheimer’s disease. Using neuroimaging together with proteomics, researchers report in the Journal of Alzheimer’s Disease that a blood test may reflect the levels of beta amyloid protein in the brain — a hallmark of the disease [1]. The findings may eventually lead to a blood test that helps to predict the risk for developing Alzheimer’s disease.

Drug for Multiple Myeloma Demonstrated to Significantly Extend Disease-Free Survival

Initial results from a large, randomized clinical trial for patients with multiple myeloma, a cancer of the blood and bone marrow, showed that patients who received the oral drug lenalidomide (Revlimid, also known as CC-5013) following a blood stem cell transplant had their cancer kept in check longer than patients who received a placebo. The clinical trial, for patients ages 18 to 70, was sponsored by the National Cancer Institute (NCI), and conducted by a network of researchers led by the Cancer and Leukemia Group B (CALGB) in collaboration with the Eastern Cooperative Oncology Group (ECOG) and the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). The BMT CTN is co-sponsored by NCI and the National Heart, Lung, and Blood Institute, both parts of the National Institutes of Health.

Pharmacogenetic Algorithm Accurately Predicts Warfarin Dosing

This article was written by Noelle K. LoConte, M.D.

Warfarin (brand name Coumadin) is one of the most commonly used anticoagulants (meaning a medication that thins the blood). It is used in a variety of medical situations, including atrial fibrillation, blood clots and when there is an increased risk of blood clotting due to genetic predisposition. When a patient is on warfarin, they need frequent blood draws to measure blood thinness and frequent dose adjustments until they have reached a stable level of blood thinning.

DNA