Dark Matter DNA Active in Brain During Day-Night Cycle

Long stretches of DNA once considered inert “dark matter” of the genome — the over 98% of DNA that doesn’t code for proteins — appear to be uniquely active in a part of the brain known to control the body’s 24-hour cycle, according to researchers at the National Institutes of Health. The findings appear in the August 14th edition of the journal Proceedings of the National Academy of Sciences [1].

Dark Matter DNA

NIH Researchers Implicate Unique Cell Type in Multiple Sclerosis

Researchers at the National Institutes of Health have found evidence that a unique type of immune cell contributes to multiple sclerosis (MS). Their discovery helps define the effects of one of the newest drugs under investigation for treating MS — daclizumab — and could lead to a new class of drugs for treating MS and other autoimmune disorders.

Neuron

Improving Anti-seizure Technology

Scientists at Johns Hopkins University are developing a new early warning system for seizures that is sensitive enough to detect imminent seizures without setting off a large number of false alarms. The software may someday be embedded in a microchip that would continually check electrical activity in the brain and launch electrical stimulation whenever a seizure is beginning to form.

Seizure

Thought for the Future: Cognitive Computing

For more than fifty years, computers have essentially been calculators with storage systems and programmable memory. Researchers at IBM are aiming to improve up that. They have been working on a cognitive computing project called Systems of Neuromorphic Adaptive Plastic Scalable Electronics (SyNAPSE). By reproducing the structure and architecture of the brain — the way various regions receive sensory input, connect to each other, and transmit motor output — the SyNAPSE project models computing systems that emulate the brain’s computing efficiency, size and power usage without being programmed.

The multi-year cognitive computing initiative to build cool, compact, cognitive computing chips that rival the functionality of the human brain while meeting extremely low power and space of the human brain combines principles from nanoscience, neuroscience and supercomputing.

The multi-dimensional research team consists of IBM researchers and collaborators from Columbia University; Cornell University; University of California, Merced; and University of Wisconsin-Madison. Now in phase 2, the project is being funded by the Defense Advanced Research Projects Agency (DARPA).

The SyNAPSE project was developed out of the Almaden Institute, an annual invitation-only forum held at IBM Research – Almaden in San Jose, California. The Almaden Institute brings together prominent, innovative thinkers from academia, government, industry, research labs and the media. The event promotes an intellectually charged, stimulating and vigorous discussion that addresses fundamental challenges at the very edge of science and technology, such as privacy, the future of work, cognitive computing, complexity, and energy storage. Partnerships born out of the Almaden Institute range from university and national laboratory collaborations to connections among IBM research labs and with industry experts, all forming a dynamic, multi-disciplinary team that focuses on unique aspects of the project.

Source: IBM

Counterfeit ADHD Medication Common On Internet, FDA Warns

While any pharmaceutical purchased online may be counterfeit, of poor quality, or both, the FDA recently warned consumers with specific regard to the prescription drug Adderall, which is used to treat attention deficit hyperactivity disorder (ADHD) [1].

Authentic vs counterfeit Adderall