TeleVox, a high-tech engagement communications company that provides automated voice, email, text and web solutions that activate positive patient behaviors through the delivery of a human touch, recently released a study combining consumer and healthcare provider opinion entitled “Healthcare Change: The Time is Now” [1]. The report, which addresses the healthcare industry’s essential shift away from primarily treating illness to keeping people healthy, reveals that the majority of healthcare practices across the country aren’t prepared to meet the demand of the 46.6 million Medicare beneficiaries who are now eligible for wellness visits.
Study Finds Few Baby Boomers Receiving, Few Healthcare Practices Prepared to Offer Medicare Wellness Visits
Q&A: Is “Wheat Flour” Whole Wheat, And Why Does It Matter?
Question: Is whole wheat considered a whole grain? As I understand it, foods with a low glycemic index are supposed to leave you feeling fuller, take longer to digest, and have health benefits. I thought whole grains were supposed to do those things too, but I’ve also read on the Internet that there’s no difference between wheat flour and white flour. What’s the truth?
Increasing Percentages of New Drugs are Failing Phase II and III Trials
In the drug discovery pipeline, Phase I trials are first used to evaluate if a new drug is safe, then Phase II trials are done to assess the drug’s efficacy, and finally Phase III trials are performed to monitor side effects and compare the drug to similar compounds already on the market. Each consecutive phase includes more people to refine the results obtained in the previous phase. A recent analysis by the Centre for Medicines Research in the UK has concluded that since 2008, the failure rate for drugs in Phase II and III clinical trials has been rising [1-2]. Phase II success rates are currently at 18%, lower than at any other phase of drug development.
Biomarker Bulletin: March 21, 2011
Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.
- MedTrust Online, Avantra Biosciences Collaborate to Involve Clinicians in Assay Development
MedTrust Online and Avantra Biosciences recently announced that they will collaborate on involving clinicians in early-stage development of molecular diagnostic assays to run on Avantra Biosciences’ QPDx multiplex immunoassay system.
- Biomarker May Prove Useful for Diagnosing Knee Injury
Researchers from Stanford University School of Medicine recently discovered a biomarker that may enable doctors to diagnose a common form of knee injury. The study, published in the Journal of Bone and Joint Surgery, has identified a specific protein complex in the knee fluid of patients with painful meniscal tears.
- OncoTrack Launches Search for Novel Genomic Cancer Diagnostics
A new European consortium called OncoTrack has just launched one of Europe’s largest collaborative academic-industry research projects to develop and assess novel approaches for the identification of new biomarkers for colon cancer. The five year project, Methods for systematic next generation oncology biomarker development, brings together top European academic researchers with a wide range of expertise and partners them with pharmaceutical companies.
- Discovery of Diagnostic and Prognostic Prostate Cancer Serum Biomarkers Guided by Cancer Genetics
An interdisciplinary team of researchers from ETH Zurich, University Hospital Zurich and the Cantonal Hospital of St. Gallenhas has defined biomarkers in patients’ blood serum that indicates the presence of prostate cancer. The method used has the potential to be applied to other types of tumors.
- SciClips Launches Diagnostic and Prognostic Biomarker Database
In the era of personalized medicine, drugs will be targeted to patients based upon his or her unique genetic profile. Biomarkers are a critical component for tailoring treatments to individual patients. Biomarkers will be used as tools for target discovery, noninvasive early stage diagnosis of diseases, for evaluation of mode of action of a drug, dose determination and prediction of the drug effect. They will accelerate not only the development of effective and non-toxic drugs but also help in monitoring patient health and response to treatment.
Panel Calls for Reducing Colorectal Cancer Deaths by Striking Down Barriers to Screening
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Despite evidence and guidelines supporting the value of screening for this disease, rates of screening for colorectal cancer are consistently lower than those for other types of cancer, particularly breast and cervical. Although the screening rates in the target population of adults over age 50, have increased from 20-30 percent in 1997 to nearly 55 percent in 2008 – the rates are still too low. An NIH state-of-the-science panel was convened this week to identify ways to further increase the use and quality of colorectal cancer screening in the United States.
“We recognize that some may find colorectal cancer screening tests to be unpleasant and time-consuming. However, we also know that recommended screening strategies reduce colorectal cancer deaths,” said Dr. Donald Steinwachs, panel chair, and professor and director of the Health Services Research and Development Center at the Johns Hopkins University. “We need to find ways to encourage more people to get these important tests.”
The panel found that the most important factors associated with being screened are having insurance coverage and access to a regular health care provider. Their recommendations highlighted the need to remove out-of-pocket costs for screening tests.