A new strategic plan to guide diabetes-related research over the next decade was announced recently by the National Institutes of Health. The plan, developed by a federal work group led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), identifies research opportunities with the greatest potential to benefit the millions of Americans who are living with or at risk for diabetes and its complications.
Neural Stem Cell Therapy for Ischemic Stroke Patients
The single largest cause of adult disability in the developed world is ischemic stroke, in which blood flow in or to the brain is blocked. It precipitates immense amounts of social and financial costs. Currently, therapies for stroke focus on prevention or acute phase treatments that arrest the stroke while it is happening. But many patients are not fortunate enough to get acute phase treatment and suffer neurological damage that leads to functional and cognitive impairment. Until now, there have been almost no options for such patients. But last February, a company called ReNeuron received approval to begin a clinical trial of neural stem cell therapy for disabled stroke patients [1]. Two patients have been treated thus far and the therapy appears to be safe.
Abnormal Heart Rate Turbulence May Predict Heart Disease
According to a study in the February 15 edition of the Journal of Cardiovascular Electrophysiology, abnormal heart rate turbulence is associated with an increased risk of heart disease death in otherwise older, low-risk individuals [1]. Additional studies need to be done in order to understand whether this potential biomarker will be a clinically valuable tool.
Blueberry Extracts Improve Insulin Sensitivity in Obese Adults
In the United States, 23.6 million children and adults — 7.8% of the population — have diabetes and one-third of U.S. adults are obese [1-2]. Obesity is associated with an increased risk of developing type 2 diabetes as well as insulin resistance, a condition that precedes the development of type 2 diabetes. New research published in the Journal of Nutrition now suggests that blueberries can help improve insulin sensitivity in obese, non-diabetic and insulin-resistant people [3].
Lifestyle Intervention Improves Risk Factors in Type 2 Diabetes
An intensive lifestyle intervention program designed to achieve and maintain weight loss improves diabetes control and cardiovascular disease risk factors in overweight and obese individuals with type 2 diabetes, according to four-year results of the Look AHEAD study, funded by the National Institutes of Health and the Centers for Disease Control and Prevention. The results are published in the Sept. 27, 2010, issue of the Archives of Internal Medicine.