Lactose Intolerance: A Diagnostic Fad

February 15, 2012 | by

Just as clothing styles come in and out of fashion, diagnoses go through fads as well. While this is rarely true of diagnoses issued by traditional healthcare practitioners, health-related Internet sites (particularly those promoting alternative medicine) and some practitioners of alternative medicine may be susceptible to these diagnostic trends. One such fad diagnosis is lactose intolerance, which is sometimes blamed for everything from hyperactivity to joint pain.

Pouring milk splashImage credit: Pouring milk splash via Shutterstock

Biomarker Bulletin: January 30, 2012

January 30, 2012 | by

Biomarker Bulletin is an occasionally recurring update of news focused on biomarkers aggregated at BiomarkerCommons.org. Biomarkers are physical, functional or biochemical indicators of normal physiological or disease processes. The individualization of disease management — personalized medicine — is dependent on developing biomarkers that promote specific clinical domains, including early detection, risk, diagnosis, prognosis and predicted response to therapy.

Biomarker Commons

Artificial Sweeteners

October 13, 2011 | by

There are a multitude of alternative sweeteners available on the market today. Some of these, like fructose, contain calories. Others — the so-called non-nutritive sweeteners — do not. While these “artificial” sugars don’t elevate blood glucose like table sugar does (which makes them more appropriate and healthy for diabetics than traditional sugar is), and while the body can’t convert them into fat, they’re not completely free of problems and complications as components of diet.

Artificial sweeteners

Crohns Disease Treatment Also Helps Protect the Gut From Infection

March 24, 2010 | by
ResearchBlogging.org

The gene Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) encodes a cytokine, a signaling molecule secreted by immune cells that has an effect on other cells and is involved in inflammation. A recent report in Cell Host and Microbe reveals that in the gut, GM-CSF helps protect against infection by a bacterial pathogen [1].

Dendritic cell

GM-CSF has long been known to promote the survival and differentiation of dendritic cells, immune cells that are present in small quantities in tissues that are in contact with the external environment, including the skin and the inner lining of the nose, lungs, stomach and intestines. Dendritic cells are immune modulators that originate in the bone marrow and travel through the blood and lymph to the peripheral tissues in an immature state. Once they arrive, they differentiate and function as professional “antigen presenting cells”: they alert T cells and B cells to the presence of any foreign invaders. The T and B cells then mount an immune response.