Lactose Intolerance: A Diagnostic Fad

February 15, 2012 | by

Just as clothing styles come in and out of fashion, diagnoses go through fads as well. While this is rarely true of diagnoses issued by traditional healthcare practitioners, health-related Internet sites (particularly those promoting alternative medicine) and some practitioners of alternative medicine may be susceptible to these diagnostic trends. One such fad diagnosis is lactose intolerance, which is sometimes blamed for everything from hyperactivity to joint pain.

Pouring milk splashImage credit: Pouring milk splash via Shutterstock

Glucosamine and Chondroitin Found to be Ineffective for Relief of Arthritis Pain

November 10, 2010 | by

For over a decade, chondroitin and glucosamine have been recommended in guidelines, prescribed by general practitioners and rheumatologists, and used by patients as over-the-counter medications to modify the clinical and radiological course of arthritis. Nevertheless, a recent meta-analysis in the British Journal of Medicine (BMJ) measuring pain intensity and joint inflammation in over 3,800 patients concludes that chondroitin, glucosamine and their combination do not reduce joint pain or have an impact on narrowing of joint space [1].

Knee cartilage

Cartilage is an elastic, fibrous connective tissue found in many areas of the human body, including the joints between bones, the elbow, the knee and the ankle. Glucosamine and chondroitin are key structural components in cartilage and are frequently prescribed to reduce joint pain and slow the progression of the disease. It has been thought that oral administration of these compounds compensates for the loss of cartilage in damaged joints. Glucosamine and chondroitin are partially absorbed in the intestine and several studies suggest that at least some of what was ingested can reach the joints. Nevertheless, the recent study, not a clinical trial itself, but a study of studies (i.e. a meta-analysis), compared glucosamine hydrochloride, glucosamine sulphate, and/or chondroitin with placebos and found that none reduced pain intensity or changed the width of joint space (i.e. reduction of inflammation) [1].