It seems to be a fact of life that memory performance decreases as we age, but new research helps to understand what precisely is decreasing, why and points towards strategies that might help. A study published in the journal Memory suggests that older adults perform less well on working memory tasks as they do not forget information that is no longer relevant [1]. This might sound like a good thing, but it leads to overload of memory processes, damaging memory performance.
Memories are Made of This: Differences in Working Memory with Age are Linked to Memory Strategies Used
Memory Enhancement Achieved in Rats
Memories are fragile; initially forming and then retrieving them are both dependent on new protein synthesis in the brain, and both processes are vulnerable to disruption. A number of agents are known that can impair memory and these can certainly be useful — for example, in treating post-traumatic stress disorder (ptsd). Enhancing memory, however, has proven more difficult. Yet as noted in The New York Times last week [1], two different research groups have recently reported enhancing memory in rats [2-3]. Of note is the fact that they did so utilizing independent molecular pathways.
Growth Factor Enhances Memory, Prevents Forgetting in Rats
A naturally occurring growth factor significantly boosted retention and prevented forgetting of a fear memory when injected into rats’ memory circuitry during time-limited windows when memories become fragile and changeable. In a study funded by the National Institutes of Health (NIH), animals treated with insulin-like growth factor (IGF2) excelled at remembering to avoid a location where they had previously experienced a mild shock [1].
Health Highlights – March 6th, 2009
Health Highlights is a biweekly summary of particularly interesting articles from credible sources of health and medical information that we follow & read. For a complete list of recommeded sources, see our links page.
- How distractible are you? The answer may lie in your working memory capacity | Cognitive Daily
Dave Munger pays attention to a recent study on memory capacity and mental focus.
- Genetics of Cancer Resistance | Dr Shock MD PhD
Dr Shock reviews fundamental concepts in genetics and highlights a study providing alternative explanations for cancer resistance.
- Why Does My Child Need a Flu Shot? | Doctor David’s Blog
Dr. David Loeb covers recent flu-related news and discusses a study on drugs designed to treat influenza. His advice: prevent the flu with a flu shot.
- FDA OKs First Human Trials of Embryonic Stem Cells – Geron Biotech | The Medical Quack
Barbara Duck reports that the Federal Drug Administration has approved the first human trials of embryonic stem cells to treat a small group of spinal cord injury patients.
- How to make EBM easy to swallow: BMJ PICO | Laikas MedLibLog
Cliff Notes for evidence-based medicine? Shamsha Damani reports that the British Medical Journal (BMJ) will be publishing summaries for published research articles.
- Reality Deniers | Science-Based Medicine
Homeopaths deny chemistry, acupuncturists and chiropractors deny anatomy, energy therapies deny our understanding of physics and energy – they all deny the validity of the scientific method.