Discover the Science of Health
A good night’s rest may literally clear the mind. Using mice, researchers showed for the first time that the space between brain cells may increase during sleep, allowing the brain to flush out toxins that build up during waking hours. These results suggest a new role for sleep in health and disease. The study was funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the NIH.
Scientists have been looking for itch-specific nerves for decades. New research from investigators at Johns Hopkins University and Yale University in the United States and several universities in China has identified sensory neurons in mice that are dedicated to relaying itchy sensations from the top layers of skin to the spinal cord [1].
By isolating cells from patients’ spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis (ALS). They found that during the disease, cells called astrocytes become toxic to nerve cells — a result previously found in animal models but not in humans. The new model could be used to investigate many more questions about ALS, also known as Lou Gehrig’s disease.
This article was written by Liz Hodge.
Most of us like a great steak, but may not want to think about how it arrives on our plate. Similarly, we want medicines, vaccines, antibiotics, surgery and diagnostic tools when we’re sick, but we may not care to know how exactly these treatments make it into our hospitals and pharmacies. Well, chances are, scientists developed them with the help of laboratory animals. Nearly every medical breakthrough involves animal research. From antibiotics to blood transfusions, dialysis to organ transplantation, vaccinations to chemotherapy, bypass surgery and joint replacement, practically every drug, treatment, medical device, diagnostic tool or cure we have today was developed with the help of laboratory animals. Each day, dedicated scientists study animals to find new cures for diseases and conditions that are currently incurable.
Spinal muscular atrophy legislation, “The SMA Treatment Acceleration Act”, will soon be introduced in both the U.S House of Representatives and the U.S. Senate.
What is spinal muscular atrophy?
Spinal muscular atrophy (SMA) is an autosomal recessive (meaning the disorder is inherited by receiving one gene from both mother and father) neuromuscluar disorder that affects motor neurons of the spinal cord and brainstem. Motor neurons are responsible for supplying electrical and chemical messages to muscle cells. Without proper input from motor neurons, muscle cells don’t function properly and become much smaller (atrophy), producing symptoms of muscle weakness and affecting the ability to swallow, breath and move limbs.
